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	Asian Journal of Andrology 2001 Dec; 3: 301-303 Gustavo F. Gonzales, Amanda Cordova, Carla Gonzales, Arturo Chung, Karla Vega, Arturo Villena Department of Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura. Universidad Peruana Cayetano Heredia, Lima, Peru Abstract: Aim: The present study was designed to determine the effect of a 4 month oral treatment with tablets of gelatinized (proprietary extrustion process) Lepidium meyenii Maca on seminal analysis in nine adult normal men aged 24-44 years old. Methods: Nine men received tablets of maca (1500 or 3000 mg/day) for 4 months. Seminal analysis was performed according to guidelines of the World Health Organization (WHO). Serum luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), testosterone (T) and estradiol (E2) were measured before and after treatment. Results: Treatment with gelatinized maca resulted in increased seminal volume, sperm count per ejaculation, motile sperm count, and sperm motility. Serum hormone levels were not modified with maca treatment. Increase of sperm count was not related to increased dose of maca. Conclusion: Maca in gelatinized form improved sperm production and sperm motility by mechanisms not related to LH, FSH, PRL, T and E2.